This article, whose main author is David Cordero, published in BMC journal, shows how the dysregulation of transcriptional programs leads to cell malfunctioning and can have an impact on cancer development. The study aims to characterize global differences between transcriptional regulatory programs of normal and tumor colon cells. The results show that the tumor network exhibits […]

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Recently, the paper Mutanome and expression of immune response genes in microsatellite stable colon cancer has been published in the Oncotarget journal. The first author is Rebeca Sanz, who has a PhD in Biology, from the Cancer Prevention and Control Program. Victor Moreno, Adriana Lopez-Doriga and Henar Alonso, among others, are also listed as authors. […]

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The article Exome Sequencing Reveals AMER1 as a Frequently Mutated Gene in Colorectal Cancer has been published in Clinical Cancer Research journal. The main author is Rebeca Sanz, from the Cancer Prevention and Control Program at ICO. The main objective of the study was to characterize the colonomicst tumors at mutational level, by exome sequencing. After analyzing the results, […]

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The article Altered pathways and colorectal cancer prognosis, published at BMC Med journal by Víctor Moreno and Rebeca Sanz-Pamplona, discusses the results published by Slattery et al. in the article “Improved survival among colon cancer patients with increased differentially expressed pathways”. The authors showed a differential gene expression analysis between tumor tissue and adjacent normal tissue based […]

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