Genetic predisposition is an important determinant of colorectal cancer (CRC), as demonstrated by the elevated frequency of this disease within the affected families. Besides the several known driver mutations of the key genes implicated in the tumorigenesis, there are also common genetic polymorphisms implicated in CRC. Each of these polymorphisms confers a small increase in […]

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During the progression of colon cancer various genetic aberrations accumulate in the DNA. One of the most common genetic alterations are anomalies in the length of the telomeres. Telomeres are repetitive DNA sequences (TTAGGG nucleotides) located at the end of chromosomes that protect the end of the chromosome from deterioration or fusion with neighboring chromosomes. […]

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The group of experts at IARC demonstrates the effectiveness of main methods for early detection of colorectal cancer and their benefits in cancer screening, as published in the New England Journal of Medicine. An international group of experts, convened by the International Agency for Research on Cancer (IARC), have carried out a systematic review and […]

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The Catalan Institute of Oncology (ICO) has completed the coverage of the Colorectal Cancer Screening Program (CCR) throughout its territory of influence. Currently, all the target population (men and women 50-69 years old) residing in Hospitalet de Llobregat, Baix Llobregat, Garraf, Alt Penedès, Barcelonès Nord and Maresme have already received at least once invitation to […]

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The European Commission is developing an initiative aimed at improving breast cancer care in Europe. The aim is to establish an accreditation system for screening units and diagnostic services for breast cancer and a platform for clinical practice guidelines for post-diagnostic care units. For this reason, the Breast Cancer Screening Unit of the Catatán Institute […]

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A safe and effective colorectal cancer (CRC) chemoprevention agent remains to be discovered. In this work we aim to evaluate the association between the use of glucosamine and/or chondroitin sulphate and risk of colorectal cancer (CRC) in the MCC-Spain study, a case-control study performed in Spain that included 2140 cases of CRC and 3950 population […]

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Colorectal cancer (CRC) screening of the average risk population is only indicated according to age. We aim to elaborate a model to stratify the risk of CRC by incorporating environmental data and single nucleotide polymorphisms (SNP). The MCC-Spain case-control study included 1336 CRC cases and 2744 controls. Subjects were interviewed on lifestyle factors, family and […]

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Researchers from Victor Moreno’s group have issued the first predictive risk model of colon and rectal cancer based on Spanish data that combines genetic and lifestyle information. Their work, published in Scientific Reports, highlights the importance of improving lifestyle to reduce the risk of colon cancer and suggests using a combination of lifestyle and genetic […]

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A new study from the Catalan Institute of Oncology has found that a particular papillomavirus lineage associated with anogenital cancers very likely originate through sexual transmission from archaic Neanderthals-Denisovans to modern humans. The study led by Ville Pimenoff at the Catalan Institute of Oncology and Ignacio Bravo at the French National Center for Scientific Research […]

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NEW STUDY TO DETECT COLORECTAL CANCER The Catalan Institute of Oncology leads a research project to improve early detection of colorectal cancer. The study,  called COLSCREEN, will be performed with the help of the following endoscopy centers:  University Hospital of Bellvitge, Viladecans Hospital and Hospital Moisès Broggi. If you want to help us, you will find more […]

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